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Department of Medicinal Chemistry

Research Activity

  • Targeting Pyruvate kinase-M2 using various drug discovery tools
  • Transition metal catalysed C-H activation reactions of unreactive C-H bond for the synthesis of anticancer and neuroprotective agents
  • Peptide/nucleobase-polymer complexes and conjugatesfluorinated biopolymers as new scaffolds for biomedical applications
  • Peptide drug conjugates, peptide self-assembly for diagnosis and drug delivery
  • Design and synthesis of heterocyclic compounds/ peptides/peptidomimetic/bio- organometallic diseases as therapeutics towards cancer, neuronal disorders and viral deseases
  • Development of new process and concepts in synthetic organic chemistry towards sustainable synthesis of NCES/APIs using green chemistry and novel methodology.
  • Re purposing of existing drug molecules for improved PK/PD profiling by modification of non pharmacophoric parts.
  • Computer aided drug designing, docking, simulation studies for (quantitative) structure activity relationship (SAR)drug repurposing and peptide/peptidomimetics mapping

Faculty

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Name Designation
Dr. Bichismita Sahu Associate Professor
Dr. Amit Shard Assistant Professor
Dr. Dinesh Kumar Assistant Professor

Post Doctoral Fellow

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Name Designation
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NMR

Instruments/Equipments

  • 500 MHz
    NMR
  • LC-HRMS
    (CIF)
  • FTIR
  • HPLC
  • Semi-Preparative
    HPLC
  • UV-VIS
    Spectrophotometer
  • Flash
    Chromatograph
  • Microwave
    Synthesizer
  • Polarimeter
  • Rotary
    Evaporator
  • Carousel
    Reaction Station
  • UV
    Cabinet
  • Melting Point
    Apparatus
  • Glovebox
  • Microwave Synthesizer
  • Peptide Synthesizer
  • Schrodinger Work-state
  • Vacfage
  • Solvent Cabinets
  • Fame hoods
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