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Department of Natural Products

Research Activity

  • Bio-prospecting of endolichenic fungi to discover novel bioactive scaffolds
  • LC-MS based dereplication strategies for isolation of natural products from microbial and plant sources
  • Fingerprinting of herbal extracts by LC-HRMS/MS-MS for chemical marker identification
  • Bioassay-guided isolation, structure elucidation and synthetic modification of bioactive compounds from medicinal plants
  • Development of analytical methods for standardization of polyherbal formulations using hyphenated techniques
  • To establish Q-markers for the quality standards of traditional Ayurvedic /herbal medicines
  • Blending the strategies of synthetic organic chemistry along with the medicinal aspects of natural products for the development of New Chemical Entities (NCEs) against Cancer and Neurodegenerative disorders
  • Total Synthesis and semi synthesis of bioactive Natural products and its structural modification via C-H functionalization and C-C coupling reactions
  • Design and construction of fluorine containing scaffolds of pharmaceutical importance via C-H Bond activation. Incorporation of Fluorine into the bioactive natural product scaffolds and its biological evaluation
  • Microbial biotransformation of bioactive sesquiterpenes scaffolds
  • Metabolomics based Natural Product profiling and discovery
  • Bioprospecting of Endophytic fungi isolated from medicinal plants for sustainable production of bioactive compounds

Faculty

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Name Designation
Dr. Abhijeet S. Kate Associate Professor
Dr. Satyasheel Sharma Assistant Professor
Dr. Siddheshwar Chauthe Assistant Professor
Dr. Ravindra Taware Assistant Professor

Post Doctoral Fellow

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Name Designation
- -
natural-products

Instruments

  • HPLC
  • LC-HRMS
    (CIF)
  • NMR
    (CIF)
  • FTIR
    (CIF)
  • Semi-Preparative
    HPLC(CIF)
  • Flash
    Chromatograph
  • Polarimeter
    (CIF)
  • UV-VIS
    Spectrophotometer(CIF)
  • Microwave
    extraction
  • Rotary
    evaporator
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