Dr. Rakesh Kumar Tekade, Ph.D.
Associate Professor , Department of Pharmaceutics
Research Interest
- Dr. Rakesh K Tekade, Assistant Professor of the Department of Pharmaceutics, is an academic-researcher with >10 year of teaching and research and postdoctoral experience gained in USA, UK, Malaysia, and India. He is recipient of several acclaimed awards including Commonwealth Fellow- UK, AICTE-National Doctoral Fellowship, IRISH-Postdoctoral Award, CSIR-SRF, AICTE-JRF. He has taken two postdoctoral Fellowships from University of Hawaii, USA and UT Southwestern Medical Centre, USA.
- Dr. Tekade’s research group at NIPER-A investigates the design, development, and characterization of targeted nanotechnology-based formulations for the site-specific delivery of therapeutic drugs, siRNA, microRNA, plasmids, and peptides for the treatment of cancer. Development of NIR-Laser activatable Nanoseeds for the treatment of cancer as well as for the prevention of post-surgical relapse of the resectable tumor is another thrust goal of his research focus. An overarching goal of his current research interests encompass development of novel polymeric nanomaterial for effective cytosolic delivery of gene therapeutics. Dr. Tekade’s research is focused on designing a new generation of nanoparticles, which could identify the cancer cells and selectively deliver anticancer drugs and genes to inhibit the growth of cancer while sparing healthy tissues. His research work involves the applications of polymer chemistry, nanotechnology, molecular biology, pharmacokinetics/pharmacodynamics and imaging techniques. His research group has also investigated the anticancer activity, Pharmacokinetics, pharmacodynamics, and molecular dynamics of several compounds and nanoformulations against cancer cell lines and tumorogenic mouse models. Till date, he haspublished >120 peer reviewed publications in international SCI indexed journals(>5000 citations; H–index of 39; cumulative Impact Factor: 395.10), contributed >90 international reference book chapters (Elsevier, Springer, Taylor & Francis and Wiley),05 invited editorial articlesand05 patent applications. He has delivered several invited researches talks and presented research finding in more than 30 scientific conferences. Till date he has mentored:02 Postdoc, 07 Ph. D, 43 Masters, 10 B. Pharm/ Biomedical Science students. Dr. Tekade is an Editor in Chief of a famous Book Series entitled “Advances in Pharmaceutical Product Development and Research Series”. As an editor, he has published Six (06) widely referred books namely: (i) Dosage Form Design Parameters, (ii) Dosage form Design Considerations, (iii) Fundamentals of Drug Delivery, (iv) Biomaterials and Bionanotechnology, (v) Drug Delivery Systems, (vi) Future of Pharmaceutical Research and Development.
- https://www.elsevier.com/catalog/pharma/pharmaceutical-science/drug-delivery/advances-in-pharmaceutical-product-development-and-research. He is expert reviewer for more than 50 peer reviewed international Journals of repute.
Experience
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Feb 2020 - Present
Associate Professor (Pharmaceutics)
NIPER-Ahmedabad (India)
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July 2019-Jan 2020
Assistant Professor
Indian Institute of Technology (IIT)- Jammu
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Aug 2014-May 2016
Lecturer in Pharmaceutical Technology
School of Pharmacy, International Medical University, Kuala Lumpur (KL), Malaysia
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Aug 2013 - Jun 2014:
Postdoctoral Fellow-II
University of Texas, UT Southwestern Medical Centre, Dallas, USA
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Jul 2011 – Aug 2013
Postdoctoral Fellow-I
University of Hawaii, College of Pharmacy, Hilo, Hawaii, USA
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Mar 2008 – Jun 2011
Senior Research Fellow (SRF-CSIR), Awarded by Council of Scientific & Industrial Research (CSIR), New Delhi, India for pursuing Ph. D, availed at Dr. Hari Singh Gour Central University, Sagar, India
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Aug 2009 – Aug 2010
Commonwealth Fellow
University of Central Lancashire, Preston, UK
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Apr 2009
National Doctoral Fellow
All India Council of Technical Education (AICTE), New Delhi, India
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Sep 2007 – Mar 2008
Scientist (F & D)
Ranbaxy Pharmaceuticals ltd, Dewas, India
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Jul 2006 – Sep 2007
Lecturer of Pharmaceutics
BITS College of Pharmacy, Bhopal, India
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2004-2006
Junior Research Fellow (JRF-AICTE ) ,Awarded by All India Council of Technical Education (AICTE), New Delhi, India for pursuing M. Pharm, availed at Dr. Hari Singh Gour Central University, Sagar, India
Honours
Honours
- Nominated Member, Board of Studies, Gujarat Forensic State University, Department of Forensic Pharmacy, Gujarat.
- rant reviewer for the FONDECYT FUNDS (Chile), National Science Centre (Poland); French National Research Agency (ANR) France, Khwarizmi International Award (KIA) (Iran).
- Member- Board of Studies and Research (NIPER-A), Member- Research advisory committee (NIPER-A), Member- Equipment purchase committee (NIPER-A), Senate Member (NIPER-A), Member- Placement Cell (NIPER-A)
- Guest Editor in chief ‘Thematic’: Current Pharmaceutical Design (Bentham Publisher), Impact factor: 3.3 (Currently serving)
- INTERNATIONAL ADVISORY BOARD MEMBERS, International Journal Of Pharmaceutical Sciences And Research. (2008-Till Date)
- Executive board Member: Int. J. Pharm. Pharma. Sci. (2009-Till Date)
- Assistant editor: American Journal of Phytomedicine and Clinical Therapeutics (2012-Till date); http://www.ajpct.org/index.php/editorial-board
- Editorial Advisory Board, Pharm Aspire Journal
- Editorial Board Member, American Journal of Pharmaceutical Sciences and Nanotechnology
- Editorial Panel Member, EC Pharmacology and Toxicology https://www.ecronicon.com/ECPT-EB.php
- EXPERT REVIEWER FOR SCIENTIFIC JOURNAL
- Chemical Reviews (ACS; IF- 52.5), J. Controlled Release (Elsevier; IF-7.8), Biomaterials (Elsevier; 8.4), Drug Discovery Today (Elsevier: IF-7.1), Nanomedicine: Nanotechnology, Biology and Medicine (Elsevier; IF-5.8), Nanomedicine London (Future Medicine;
IF-4.8), Biomaterial Science (Springer; IF-4.8), Molecular Pharmaceutics (ACS; 4.5), European J. Pharmaceutical Sciences (Elsevier; IF-4.5), J. Biomedical Nanotechnology (American Scientific Publishers; 4.5), Bioorganic Chemistry (Elsevier; IF-3.9), International
Journal of Pharmaceutics (Elsevier; IF-3.7) to name the few
Awards
- Early career research Award (ECRA) – 2018, DST-SERB
- Best Poster Award -2014: Royal Chemical Society, UK-Malaysia Joint Conference, Malaysia
- Research Travel Award, Society of Nuclear Medicine Conference, The University of Texas- USA- 2014 ,Awarded to selected applicants by significance of work by UTSW panel-USA
- IRISH Research Council Government Postdoctoral Award- 2013, One of most competitive fellowship awarded by Govt. of Ireland
- Travel Grant, Controlled Release Society Conference- The University of Hawaii, USA- 2013 ,Awarded to selected postdoctoral fellows by Hawaiian CRS Chapter-USA
- Young Scientist Award- 2012: 1st International Conference on Pharmacy and Pharmaceutical Sciences, Bhopal-India
- Commonwealth Fellowship, British Council-London, UK- 2008-2009, Awarded to 4 Pharmacists from India to pursue Ph.D. work in UK
- Travel Grant, Int. Conference on Biomedical Application of Dendrimer, France- 2009, Awarded by University of Central Lancashire, UK to present research work
- Senior Research Fellowship, Council for Scientific and Industrial Research, New Delhi, India- 2008-2012, One of India’s most prestigious scholarship (Funded for Ph.D. research work)
- Best paper award ,Mottan Devi Dandiya Trust, India, Awarded for publication in Chemical Reviews 2009-2010 (Impact factor-44.66)
- National Doctoral Fellowship, All India Council of Technical Education, New Delhi, India, declined- 2009, One of India’s most prestigious scholarship
- Junior Research Fellow (M. Pharm ) ,All India Council of Technical Education, New Delhi, India, 2004-2006
Grants
- Aptamer-targeted dendronized polymeric nanoparticles to deliver Anti-miRNA fortreatment of Triple Negative Breast Cancer, 50 Lakh, DST, SERB India- 2017, Ongoing, Role: PI
- Triple punch approach for triple negative breast cancer by delivering siRNA anddoxorubicin using graphene oxide wrapped polymeric nanoparticles, 20 Lakh, DST, SERB India- 2017, Ongoing, Role: Primary Supervisor
- A novel strategy to explore endosomal degradation of gene therapeutics, 133,000 Malaysian RM(22 Lakh INR) Fundamental Research Grant Scheme, Ministry of Health, Malaysia, 2016, Ongoing, Role: PI
- Synthesis and characterization of MTX conjugated gold nanocapsules for cancer Therapy, 12,000 Malaysian RM (2 Lakh INR) IMU-JC, Graduate Research Grant, Kuala Lumpur- Malaysia- 2015, Completed, Role: PI
- Formulation Development And Evaluation Of Aloe Vera/gold loaded Alginate-Gelatin Composite Film For Wound Healing Activity, 12,000 Malaysian RM, (2 Lakh INR) IMU-JC, Graduate Research Grant, Kuala Lumpur- Malaysia-2015, Completed, Role: Co-PI
- Anticancer activity of hybrid silver-graphene oxide nanocomposites, 12,000 Malaysian RM (2 Lakh INR) IMU-JC, Graduate Research Grant, Kuala Lumpur- Malaysia, 2015, Completed, Role: Co-PI
- To evaluate anti-proliferative potential of dendrimer stabilized lipid vesicular packets of paclitaxel against Lung Cancer cell lines 3,000 Malaysian RM (50000 INR) Biomed Research Grant, IMU, Kuala Lumpur, Malaysia-2014, Completed, Role: PI
- To evaluate anti-proliferative activity of andrographolide microemulsion in cancer cell lines, 3,000 Malaysian RM (50000 INR) Biomed RES Grant, IMU, Kuala Lumpur, Malaysia, 2014, Completed, Role: Co-PI
- Development of Gold nanoprobe for imaging and therapy for prostate cancer, 45,500 US $, University of Texas, UT Southwestern, Medical Centre- Dallas, USA, 2014, Completed, Role: PI
- Development of Hybrid Nanocarrier for Mesothelioma Therapy, 44,000 US $, The University of Hawaii, Hilo, USA, 2013, Completed, Role: PI
- Synthesis and evaluation of folate-targeted dendrimer as anti-cancer drug carrier, 21,000 GBP, Commonwealth Commission, London, UK, 2009, Completed, Role: PI
- Formulation of dendrimer-based targeted anticancer formulation, 38,0,000 INR, Council for Scientific and Industrial Research, New Delhi, India, 2008, Completed, Role: PI
- Investigation of receptor upregulation and cancer targeting strategy, 14,0,000 INR, All India Council for Technical Education, New Delhi, India, 2004, Completed, Role: PI
Consultancies
- Industrial consultancy project for the development of sustained releasing formulation of natural extract, 70,000 Malaysian RM (12 Lakh INR) InQ Pharmaceuticals, Malaysia, 2015, Completed Role: Co-PI