Honours

• Selected for POSTER PRESENTATION at University of California, San Francisco in the 16th International Meeting on Human Genome Variation and Complex Genome Analysis (HGV2015) and granted a full scholarship to attend this meeting without charge.
• Award of Excellence (My Best Mentee) from SRM Medical College Hospital & Research Centre, Tirchy, Tamilnadu in the 6th National Workshop on Research Methodology, organized on 20th to 23rd March, 2019
• Awarded Certificate of Appreciation for Best activity performer-Fund Raising for Research from SRM Medical College Hospital & Research Centre, Tirchy, Tamilnadu in the 6th National Workshop on Research Methodology, organized on 20th to 23rd March, 2019.
• Awarded Certificate of Appreciation for outstanding and selfless contribution towards the nation during COVID-19 pandemic from National Institute of Pharmaceutical Education and Research, Ahmedabad (NIPER-A)

Publications

1. Santosh Kumar Behera, Nazmina Vhora, Darshan Contractor, Amit Shard, Dinesh Kumar, Kiran Kalia, Alok Jain (2021). Computational drug repurposing study elucidating simultaneous inhibition of entry and replication of novel corona virus by Grazoprevir. Nature Scientific Reports. 11(1):7307 (2021). https://doi.org/10.1038/s41598-021-86712-2. Impact Factor: 4.996. (ISSN: 2045-2322).
2. Chamoli A, Gosavi AS, Shirwadkar UP, Wangdale KV, Behera SK, Kurrey NK, Kalia K, Mandoli A (2021). Overview of oral cavity squamous cell carcinoma: Risk factors, mechanisms, and diagnostics. Oral Oncol. 121:105451. doi:
   10.1016/j.oraloncology.2021.105451. Epub ahead of print. PMID: 34329869. Impact Factor: 5.972. (ISSN:1368-8375).
3. Sahu B, Behera SK, Das R, Dalvi T, Chowdhury A, Dewangan B, Kalia K, Shard A(2022). Design and in-silico screening of Peptide Nucleic Acid (PNA) inspired novel pronucleotide scaffolds targeting COVID-19. Current Computer-Aided Drug Design. 18(1):26-40. DOI: 10.2174/1573409916666200923143935. Impact Factor: 1.606. (ISSN: 1875-6697).
4. Chaitrali Shevkar; Ashwini Armarkar; Ramani Weerasinghe; Kasun Maduranga; Komal Pandey; Santosh K Behera; Kiran Kalia; Priyani Paranagama; Abhijeet S Kate (2022). Cytotoxic Bioxanthracene and Macrocyclic Polyester from Endolichenic Fungus Talaromyces pinophilus: In-Vitro and In-Silico Analysis. Indian Journal of Microbiology.62(2):204–214. https://doi.org/10.1007/s12088-021-00994-8. Impact Factor: 2.461. (ISSN: 0046-8991).
5. Suchita D Shinde , Kamya B Rao , Santosh K Behera , Neha Arya , Bichismita Sahu (2022) Epithelial cell adhesion molecule (EpCAM) binding short peptides derived from antibody MOC-31; De-novo design, synthesis and their in-vitro evaluation. Biochemical and Biophysical Research Communications. 600:1-5. doi: 10.1016/j.bbrc.2022.01.120. Impact Factor: 3.322. (ISSN: 0006-291X).
6. Chandra Sekhar Tripathy, Anil Kumar, Ghassem Habibi Bibalani, Santosh Kumar Behera, Santanu Kumar Budhia, P K Mohanta, Easter Khura, Asadollah Asadi, Arash Abdolmaleki, Muhammad Akram, Debasish Mishra, Deepak Bhattacharya (2022). Psoriasis Vrs Cassia Fistula: In-Silico Study. Saudi Journal of Medicine, 7(3): 148-158. DOI: 10.36348/sjm.2022.v07i03.005 Impact Factor: 1.5 (ISSN: 2518-3397).
7. Sutapa Mahata, Santosh Kumar Behera, Sunil Kumar, Pranab Kumar Sahoo, Sinjini Sarkar, Vilas D. Nasare (2022). In-silico and In-vitro investigation of STAT3-PIM1 heterodimeric complex: its mechanism and inhibition by curcumin for cancer therapeutics. International Journal of Biological Macromolecules, 208:356-366 DOI: 10.1016/j.ijbiomac.2022.03.137 Impact Factor: 8.0. (ISSN: 0141-8130).
8. Ramani H. Weerasinghe, Chaitrali D. Shevkar, Kasun Maduranga, Komal H. Pandey, Renuka N. Attanayake, Abhijeet S. Kate, Gothamie Weerakoon, Santosh K. Behera, Kiran S. Kalia, Priyani A. Paranagama(2022), Bioprospecting of an Endolichenic Fungus Phanerochaete sordida Isolated from Mangrove-Associated Lichen Bactrospora myriadea. Journal of Chemistry, vol. 2022, Article ID 3193689, 11 pages, 2022. https://doi.org/10.1155/2022/3193689. Impact Factor 3.95. (ISSN: 2090-9071).
9. Chandra Sekhar Tripathy, Anil Kumar, Santosh Kumar Panda, Santosh Kumar Behera, Gaurav Giri, Asadollah Asadi, Santanu Kumar Budhia, Arash Abdolmaleki, Easter Khura, P K Mohanta, Muhammad Akram, Deepak Bhattacharya (2022). Osteosarcoma’s STAT-3 Vrs Kaempferia parviflora’s Compounds: Possible Drug Candidates. Research Journal of Pharmacology and Pharmacy6:1-15 DOI: 10.28933/rjpp-2022-01-1805 (ISSN:2572-8377).
10. Sunil Kumar, Khurshid Ahmad, Santosh Kumar Behera, Dipak T. Nagrale, Anurag Chaurasia, Manoj Kumar Yadav, Sneha Murmu, Yachana Jha, Mahendra Vikram Singh Rajawat, Deepti Malviya, Udai B. Singh, Raja Shankar, Minaketan Tripathy and Harsh Vardhan Singh (2022). Biocomputational Assessment of Natural Compounds as a Potent Inhibitor to Quorum Sensors in Ralstonia solanacearum. Molecules, 27(9), 3034. DoI:10.3390/molecules27093034. Impact Factor 4.588 (ISSN: 1420-3049).
11. Tambe, Vishakha; Patel, Sagarkumar; Shard, Amit; Behera, Santosh; Polaka, Suryanarayana ; Anup, Neelima ; Gadeval, Anuradha ; Kalia, Kiran ; Tekade, Rakesh(2022). Dendronized Polymeric Biomaterial for Loading, Stabilization, and Targeted Cytosolic Delivery of microRNA in Cancer Cells. ACS Applied Bio Materials, 2022, 5(9), 4128–4153, DOI: 10.1021/acsabm.2c00179. Manuscript ID: mt-2022-001796.R1. Impact Factor 3.95 (ISSN:2576-6422).
12. De S, Aamna B, Sahu R, Parida S, Behera SK*, Dan AK (2022). Seeking heterocyclic scaffolds as antivirals against dengue virus. European Journal of Medicinal Chemistry; 240:114576. doi: 10.1016/j.ejmech.2022.114576. Epub ahead of print. PMID: 35816877; PMCID: PMC9250831. Impact Factor 7.088 (ISSN: 0009-4374).
13. Santosh Kumar Behera, Amrita Kumari Panda, Rojita Mishra, Arabinda Mahanty & Satpal Singh Bisht (2022): Structure based virtual screening and molecular dynamics of natural anti-biofilm compounds against SagS response regulator/sensor kinase in Pseudomonas aeruginosa, Journal of Biomolecular Structure and Dynamics, 22:1-16 DOI:10.1080/07391102.2022.2100482. Impact Factor: 5.235. (ISSN: 1538-0254).
14. Chandra Sekhar Tripathy, Santosh Kumar Behera, Anil Kumar, Asadollah Asadi, Santosh Kumar Panda, GauravGiri (2022). Colorectal Cancer Vrs Glycyrrhiza glabra – Computational Docking & DFT Analysis vis-à-vis TNIK Receptor Protein. International Journal of Innovative Science and Research Technology, 7(7):38-50. DOI:10.5281/zenodo.6865162 (ISSN: 2456-2165).
15. Chandra Sekhar Tripathy, Anil Kumar, Santosh Kumar Behera, Muhammad Akram, Asadollah Asadi, Arash Abdolmaleki, Amir Mohammad Ostovar-Abarghoee, Easter Khura, Pabitra Kumar Mohanta, Santanu Kumar Budhia, Deepak Bhattacharya (2022). DengueVrsEllagic Acid & Ferric Carboxymaltose: InSilico (2022). Saudi Journal of Biomedical Research (SJBR). 7(7): 211-218. DOI: 10.36348/sjbr.2022.v07i07.001(ISSN: 2518-3214).
16. Aamna B, Kumar Dan A, Sahu R, Behera SK*, Parida S (2022). Deciphering the signaling mechanisms of β-arrestin1 and β-arrestin2 in regulation of cancer cell cycle and metastasis. J Cell Physiol. 237(10):3717-3733 doi: 10.1002/jcp.30847. Epub ahead of print. PMID: 35908197. Impact Factor: 6.513. (ISSN: 1097-4652).
17. Shinde, Sangita; Satpute, Dinesh; Behera, Santosh*; Kumar, Dinesh (2022). Computational Biology of BRCA2 in Male Breast Cancer, Through Prediction of Probable nsSNPs, and Hit Identification. ACS Omega 2022, 7(34), 30447–30461Impact Factor: 4.132. doi: 10.1021/acsomega.2c03851 (ISSN: 2470-1343 (print); 2470-1343) Manuscript ID: ao-2022-038519.R2.
18. Nishant Sharma, Ritu Soni, Monika Sharma, Sayan Chatterjee, Nidhi Parihar, Mohd Mukarram, Ruhi kale, Adil Ali Sayyed, Santosh Behera, Amit Khairnar (2022). Chlorogenic Acid: a Polyphenol from Coffee Rendered Neuroprotection Against Rotenone-Induced Parkinson’s Disease by GLP-1 Secretion.” Molecular Neurobiology 59(12): 6834-6856. doi: 10.1007/s12035-022-03071-3. Manuscript #MOLN-D-22-00368R2- [EMID:1448b78ff8ae4d19]. Impact Factor: 5.682. (ISSN:1559-1182).
19. Krishna Kumar Das, Smaranika Pattnaik*, Santosh Kumar Behera (2022). Application Of Actinomycetes In Secondary Metabolites Production: An Overview. International Journal for Research Trends and Innovation (JETIR), 9(9); b150-b169. (ISSN-2349-5162)
20. Krishna Kumar Das, Smaranika Pattnaik*, Santosh Kumar Behera (2022). Conventional Antibiotics from Actinomycetes: A mini review. IJRTI, 7(9):487-495. | ISSN: 2456-3315.
21. Krishna Kumar Das, Smaranika Pattnaik*, Santosh Kumar Behera (2022). Identification and Genomic study of the biopotent actinomycetes species Microbacterium Barkeri (LMA4): a computational approach. International Journal of Research And Analytical Reviews (IJRAR) 9(4): 845-858. (E-ISSN 2348-1269, P- ISSN 2349-5138)
22. Chandra Sekhar Tripathy, and Santosh Kumar Behera*(2022). Molecular Screening, Docking and DFT Study of Phytochemicals from Sesbania grandiflora against HER 2 Protein of Oral Cancer. Sch Int J Tradit Complement Med, 5(10): 189-198. (E-ISSN 2617-3891).
23. Lakshmi VineelaNalla, Anil Dharavath, Santosh Kumar Behera, Amit Khairnar (2023). Alpha mangostin inhibits proliferation, migration, and invasion of human breast cancer cells via STAT3 inhibition. Advances in Cancer Biology-Metastasis, 7, 2023, 100089. https://doi.org/10.1016/j.adcanc.2023.100089. (E-ISSN: 2667-3940).
24. Lingaraj Murmu, Krishna Kumar Das, Santosh Kumar Behera (2023). In-silico Evaluation of SNPs and Molecular Modelling Study in Dengue. Saudi Journal of Medicine, 8(3): 85-98. DOI: 10.36348/sjm.2023.v08i03.004. ISSN 2518-3389 (Print).

Book Chapters:

1. Krishna Kumar Das, Samapati Swagatika, Smaranika Pattnaik, Santosh Kumar Behera (2021). Chapter-17: Genomic Analysis of Psoriatic Arthritis through Computational predictions. First Edition, Biotechnology and Bioinformatics- Recent Trends. Himalay Publishing House. pp165-177.
2. Kuldeep Rajpoot, Nimeet Desai, Hari Priya Koppisetti, Muktika Tekade, Mukesh Chandra Sharma, Santosh Kumar Behera, Rakesh Kumar Tekade. “Chapter 14 – In silico methods for the prediction of drug toxicity” in Pharmacokinetics and Toxicokinetic Considerations : Volume 2 in Advances in Pharmaceutical Product Development and Research(1st ed.) Rakesh Tekade (Ed.), Elsevier Academic Press 2022, pp. 357-383. ISBN: 978-0-323-98367-9 doi.org/10.1016/B978-0-323-98367-9.00012-3
3. Suchita Dattatray Shinde, Bichismita Sahu, Ambika Chamoli, Amit Mandoli, Kiran Kalia, Santosh Kumar Behera, Chapter 9 – Tyrosine kinases: their role in hepatocellular carcinoma,Editor(s): Ganji Purnachandra Nagaraju, Ramakrishna Vadde, Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 2, Academic Press,2022,Pages 133-148, ISBN 978-0-323-98807-0, https://doi.org/10.1016/B978-0-323-98807-0.00010-7.
4. Suchita Dattatray Shinde, Neeraj Kulkarni, Bichismita Sahu, Kiran Kalia, Santosh Kumar Behera, Chapter 10 – Role of transcription factors in hepatocellular carcinoma, Editor(s): Ganji Purnachandra Nagaraju, Ramakrishna Vadde, Theranostics and Precision Medicine for the Management of Hepatocellular Carcinoma, Volume 2, Academic Press, 2022, Pages 149-163, ISBN: 978-0-323-98807-0 https://doi.org/10.1016/B978-0-323-98807-0.00007-7.
5. Smaranika Pattnaik, Santosh Kumar Behera, Niranjan Behera. Chapter-18: Molecular docking studies between components of eucalyptus essential oil and homologically modeled target protein. Editor(s): Sanket Joshi, Susmita Mukherjee, Moupriya Nag, In Advances in Biotechnology and Bioengineering, Contemporary Medical Biotechnology Research for Human Health, A volume in Advances in Biotechnology and Bioengineering. Elsevier Academic Press. Pages 169-176 ISBN: 978-0-323-91251-8. https://doi.org/10.1016/B978-0-323-91251-8.00014-3.
6. Aakanchha Jain, * Shiv Kumar Prajapati, Dolly Jain, Richa Jain, Amrita Kumari Panda, Nagma Parveen, Satpal Singh Bisht and Santosh Kumar Behera (2023). Therapeutic Nanocarriers in Cancer Treatment, 2023, 1-30. Chapter1: Cancer Biology. Current Molecular Pharmacology, 2022, 1-30 Bentham Science Publishers Ltd. Pages 11-33 ISBN: 978-0-323-91251-8.
7. Bhakti Pawar, Santosh Kumar Behera, Muktika Tekade,Nizar Al-Shari, Rakesh Kumar Tekade (2023).Chapter-9: Computer aided technologies in Drug Discovery and toxicity prediction. Elsevier Academic Press.

Expertise

Working on interdisciplinary research with special emphasis to health and mankind that could be of translational states the uniqueness of my expertise. My emphasis on communicable (Malaria, Dengue and COVID-19), non-communicable diseases (Type 2 diabetes (T2D)) and cancer. I had repurposed grazoprevir and simeprevir as antiviral drugs during COVID-19 pandemic. Pertaining to T2DM I had explored Leptin gene as the hub gene which was unexplored in GWAS and its nsSNP’s which could be a potential genetic marker for T2D therapeutics in Indian population. Explored Hydrastine and Artocarpin with better anti-cancerous activity through in-silico and in-vitro studies. Unzipped the importance of STAT3-PIM1 interaction in Triple Negative Breast cancer. My vision always will be bridging the gap and drawing a flow chart to correlate In-silico, In-vitro and In-vivo studies through establishment of state-of-the art central instrumentation facilities for the betterment of science & society.

Achievements

• Received a grant for “KARYASHALA” scheme (AV/KAR/2022/0457) from Science &Engineering Research Board (SERB) and successfully organized “High-EndWorkshop (KARYASHALA): Hands-on Implementation of Advanced Techniques in Pharmaceutical Sciences” from 17th to 23rd January,2023.
• NCBI GeneBank Submissions: 22 nos.
• One of the images from research paper entitled “Dendronized Polymeric Biomaterial for Loading,Stabilization, and Targeted Cytosolic Delivery of microRNA in Cancer Cells” was published as cover artin ACS Applied Bio Materials, 2022, 5(9), 4128–4153.
• Guest faculty to various Universities (Berhampur University, UtkalUniversity, Centurian University of technology and management, SOA University).
• Organized various workshop-cum-training programme/ short-term andl ong-term training programmes on Bioinformatics/Health Informatics to the medical professionals/ faculties and researchers.
• Selected and attended ten short term/ professional training programmes in Bioinformatics and biological sciences.
• Invited speaker to various workshops/Seminars/Training programmes organized at national and international level.
• Project approved in SAC (ICMR-RMRC) (2017) “Network pharmacology approach for identifying bioactive compounds from Carica papaya for severe dengue cases”
• Selected as a summer trainee at CSIR-CCMB, Hyderabad (2002).